This topic area builds on results from the AQUACROSS Assessment Framework to select and develop modelling approaches for the projected changes in drivers and pressures, and runs model scenarios for the case studies. Models to project and forecast impacts of drivers of change on aquatic biodiversity, ecosystem functions and ecosystems service delivery and uncertainty are selected, followed by the development of scenarios through participatory processes and assessment of the impacts of projected drivers in case study areas. Results are then evaluated in order to provide feedback to and update the Assessment Framework, provide policy recommendations on the application of the framework, and insights for the advancement of theory.